Alpha Fetoprotein
Alternate Names : AFP, Fetal Alpha Globulin
Definition A test that measures the amount of alpha fetoprotein (AFP) in serum (blood).
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Why is the Test Performed?
AFP is a protein normally produced by the liver and yolk sac of a fetus. AFP levels decrease soon after birth; AFP probably has no normal function in adults.
AFP is measured to:
- diagnose or monitor fetal distress or fetal abnormalities
- diagnose some liver disorders
- screen for and monitor some cancers.
During pregnancy, this test, along with the examination of amniotic fluid (amniocentesis), can help detect fetal spina bifida or other defects of the fetus' neural tube associated with elevated levels of AFP.
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