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Acquired Platelet Function Defect
Alternate Names : Acquired Disorders of Platelet Function, Acquired Qualitative Platelet Disorders
DefinitionAcquired platelet function defects are non-hereditary diseases or associated conditions that cause the platelets (the blood cells essential for coagulation) to not function properly.
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Overview, Causes, & Risk Factors
Platelets are blood cells that are essential for blood clotting. Platelet disorders can include inappropriate number of platelets (too many or too few), or normal number but inappropriate functioning of the platelets. Any platelet disorder affects blood clotting.
Disorders of platelet function can be caused by congenital diseases or acquired conditions. Acquired platelet function disorders are disorders of inappropriate platelet function, and that develop as a result of another disease or condition (acquired). In many cases, the platelet count may be normal or even elevated, but evidence of a bleeding disorder will be present. Myeloproliferative disorders such as primary thrombocytopenia, polycythemia vera, chronic myelogenous leukemia, and myelofibrosis can produce abnormalities in platelet function.
Other causes include renal failure, multiple myeloma, and medications such as aspirin and other anti-inflammatory medications, penicillins, phenothiazines, and prednisone (prolonged use).
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• Definition
• Overview, Causes, & Risk Factors
• Symptoms & Signs
• Prevention
• Diagnosis & Tests
• Treatment
• Prognosis
• Complications
• Calling Your Health Care Provider
• Pictures & Images
Topics that might be of interest to you Diseases & Conditions
• Acute Kidney Failure
• Anemia
• Chronic Myelogenous Leukemia (CML)
• Multiple Myeloma
• Polycythemia Vera
• Primary Myelofibrosis
• Thrombocytopenia
Tests & Exams
• Bleeding Time
• Dialysis
• Partial Thromboplastin Time (PTT)
• Platelet Aggregation Test
• Platelet Count
• Prothrombin Time (PT)
Other Topics
• Bleeding
• Bleeding Into the Skin
• Bloody or Tarry Stools
• Gastrointestinal Bleeding
• Menstrual Periods - Heavy, Prolonged, or Irregular
• Nausea and Vomiting
• Nosebleed
• Rashes
• Urine - Abnormal Color
• Urine - Bloody
• Vaginal Bleeding Between Periods
• Vomiting Blood
Review Date : 8/18/2003
Reviewed By : Corey Cutler, M.D., M.P.H., F.R.C.P.C, Department of Medical Oncology, Dana-Farber Cancer Institute; Instructor in Medicine, Harvard University, Boston, MA. Review provided by VeriMed Healthcare Network.
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