5'-N'Tase
Alternate Names : 5'-NT, 5-Nucleotidase
Definition A test that measures the amount of 5-N'Tase in the blood.
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Why is the Test Performed?
Serum 5'-N'Tase is measured as an indicator of liver damage resulting primarily from interference with the secretion of bile. Serum 5'-N'Tase is not as sensitive as some other enzymes (for example, ALP, AST, and ALT) to liver damage, but it is a more liver-specific enzyme . The level of this enzyme parallels alkaline phosphatase (ALP). It is used mostly to differentiate elevations in the above enzymes due to liver damage from damage to skeletal muscle (another cause of elevated ALP, AST and ALT).
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